DENTAL EMERGENCY? telephone call 833-925-8326
Arestin (per site): Code D4381

FDA approved subgingival delivery devices containing antimicrobial medication(s) are inserted into periodontal pockets to suppress the pathogenic microbiota. These devices slowly release the pharmacological agents so they can remain at the intended site of action in a therapeutic concentration for a sufficient length of time.


If you live in Southern California, feel free to Schedule a New Patient Visit with us in Zak Dental offices in Agoura HillsCovina/San DimasDowneyLong BeachNorth ParkSan DiegoSanta BarbaraSimi ValleyTemeculaValenciaVentura, and Whittier/La MiradaCalifornia.

For all your dental needs, schedule an appointment by calling the Zak Dental office at 833-ZAK-TEAM.


Here are some frequently asked questions (FAQ) about Arestin:

What is Arestin?

Arestin is a prescription antibiotic treatment that comes in the form of microspheres containing minocycline. It is used as an adjunctive therapy for the treatment of periodontal disease.

How does Arestin work?

Arestin is applied directly to the affected periodontal pocket by the dentist. The minocycline in Arestin is an antibiotic that helps to kill bacteria associated with periodontal disease, reducing inflammation and promoting healing.

When is Arestin prescribed?

Arestin is typically prescribed in conjunction with scaling and root planing (a deep cleaning procedure) for patients with periodontal disease. It is used to target and eliminate bacteria in the periodontal pockets.

How is Arestin applied?

The dentist or dental hygienist will apply Arestin by placing the minocycline microspheres directly into the periodontal pockets after a scaling and root planing procedure. The microspheres release the antibiotic over time.

Is Arestin painful during or after application?

The application of Arestin is typically not painful. The microspheres are inserted into the pockets, and patients may feel slight pressure during the procedure. After application, there may be mild discomfort or sensitivity that usually subsides quickly.

How long does Arestin stay active?

Arestin releases minocycline over time, providing antimicrobial effects for up to 21 days after placement. This extended release helps to combat bacteria in the periodontal pockets between dental visits.

Are there any side effects of Arestin?

As with any medication, there can be side effects. Common side effects may include temporary tooth sensitivity, a metallic taste, or sore gums. It’s essential to inform your dentist of any allergies or potential concerns.

Can Arestin be used for all cases of periodontal disease?

Arestin is often recommended for localized treatment of periodontal pockets. Your dentist will assess the severity and location of your periodontal disease to determine if Arestin is a suitable option for your case.

Is Arestin a substitute for regular dental cleanings?

No, Arestin is not a substitute for regular dental cleanings. It is used as an adjunctive treatment in combination with scaling and root planing. Regular professional cleanings and good oral hygiene practices are essential for long-term oral health.

How much does Arestin cost?

The cost of Arestin can vary depending on factors such as the number of sites treated and geographic location. It’s recommended to discuss the cost with your dentist and check with your dental insurance provider for coverage details.

Can pregnant or breastfeeding women use Arestin?

It’s essential to inform your dentist if you are pregnant, planning to become pregnant, or breastfeeding. The decision to use Arestin in such cases will be made based on the potential risks and benefits.

Is Arestin effective in treating periodontal disease?

Arestin has been shown to be effective in reducing bacterial infection and inflammation in periodontal pockets when used as part of a comprehensive periodontal treatment plan. Its effectiveness may vary from patient to patient.

Always consult with your dentist or dental professional for personalized advice and information about the use of Arestin in your specific case.